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Autor: C. Cannon Wydawnictwo: Humana Press Data wydania: 1999 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-552-2 Ilość stron: 0 Cena : 583.1 zł | |
Defining and illustrating the new paradigm of acute coronary syndromes, this text presents the management of disease including aggressive thrombolytic, andithrombotic and interventional approaches. więcej... | ||
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Autor: N. Skolnik Wydawnictwo: Humana Press Data wydania: 2007 Kategoria: medycyna i zdrowie ISBN: 978-1-588-29508-8 Ilość stron: 0 Cena : 298.9 zł | |
Filling an important gap in the primary care literature, this book provides the family practitioner with concise, yet complete summaries, of the most important national clinical guidelines. This book distills all of the leading clinical guidelines into a reader-friendly format that encapsulates the most current knowledge about best practices. About 40 of the most important clinical problems seen in primary care are covered. This book will become the essential daily reference for all primary care practitioners. więcej... | ||
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Autor: M. Strege Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: popularnonaukowe ISBN: 978-1-58829-017-5 Ilość stron: 0 Cena : 416.5 zł | |
Expert academic and pharmaceutical researchers describe their best capillary electrophoresis techniques for protein and peptide analysis. The authors present cutting-edge techniques for both capillary coatings and analytic detection via laser-induced fluorescence, for the development and commercialization of biopharmaceuticals, and for affinity capillary electrophoresis in the evaluation of protein binding, including the use of protein charge ladders. Areas of special interest covered include combining CE and capillary isoelectric więcej... | ||
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Autor: Howl Wydawnictwo: Humana Press Data wydania: 2005 Kategoria: popularnonaukowe ISBN: 978-1-58829-317-6 Ilość stron: 0 Cena : 308.7 zł | |
Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools więcej... | ||
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Autor: Kambin Wydawnictwo: Humana Press Data wydania: 2005 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-522-4 Ilość stron: 0 Cena : 583.1 zł | |
This authoritative and highly illustrated guide to arthoscopic and endoscopic surgery describes and illustrates state-of-the-art techniques and approaches that are currently used for the treatment of painful spine pathologies and the prevention of postsurgical failed back syndrome. The authors demonstrate step-by-step how minimally invasive techniques are performed in spinal surgery and how anatomical structures appearing through an endoscope can help in the diagnosis and recognition of various anatomical structures of the więcej... | ||
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Autor: M. Hanausek Wydawnictwo: Humana Press Data wydania: 1998 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-380-1 Ilość stron: 0 Cena : 459.6 zł | |
A much-needed collection of cutting-edge methods for the detection and discovery of new cancer markers, particularly molecular tumor markers. Each method is fully described by a hands-on expert who regularly uses it in the laboratory and has perfected it to a high degree of ready reproducibility. Special emphasis is given to statistical considerations in the analysis of tumor markers, recent discoveries in the field of serum and tissue marker proteins, cytogenetic markers, molecular markers, and markers for the early detection więcej... | ||
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Autor: Rosanna Peeling,Frederic Sparling Wydawnictwo: Humana Press Data wydania: 1998 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-535-5 Ilość stron: 0 Cena : 410.6 zł | |
A comprehensive collection of cutting-edge molecular protocols for the laboratory diagnosis and study of sexually transmitted diseases, including HIV. The methods-each crafted by a leading expert for comprehensiveness and genuine laboratory utility-cover the major sexually transmitted pathogens, including Neisseria gonorrhoeae, Chlamydia trachomatis, Haemophilius ducreyl, Treponema pallidum, and herpes simplex. Additional molecular techniques are included for detecting the genital mycoplasmas, hepatitis B virus, HIV-1, human więcej... | ||
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Autor: Wolfgang Walz Wydawnictwo: Humana Press Data wydania: 1999 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-540-9 Ilość stron: 0 Cena : 455.7 zł | |
Wolfgang Walz and a panel of leading authorities illuminate those cellular and molecular mechanisms brought into play during a stroke that lead to neuronal dysfunction. Such damaging factors as spreading depression waves and postischemic depolarization, cell swelling, calcium overload, and oxygen radicals leading to necrosis and apoptosis are described in detail. Also examined are the body's repair mechanisms involving altered gene expression that lead to trophic factor production and heat shock protein synthesis, as well więcej... | ||
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Autor: Bronchud Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-581-2 Ilość stron: 0 Cena : 524.3 zł | |
Award winning basic scientists and clinical researchers summarize the wealth of new molecular knowledge that sees cancer as a "disease process" involving key regulatory pathways. Emphasizing prevention, early diagnosis, prognosis, and treatment, these authoritative experts from around the world illuminate the variety of molecular markers to be found, interpret what is known about diseased regulatory pathways, and examine those future research directions likely to realize the promise of molecular therapy. From their więcej... | ||
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Autor: Reith Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-608-6 Ilość stron: 0 Cena : 528.2 zł | |
A team of leading experts comprehensively review and synthesize the most recent advances in our understanding of the role of cerebral signaling in neuronal and cerebral function. The authors emphasize the functional role of the various signaling pathways in memory, apoptosis and degeneration, depression, and drug dependence in both health and diseased states. By taking full advantage of the newfound ability to selectively remove, reduce, or enhance specific components of the signaling pathways, the investigators writing więcej... | ||
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Autor: S. Brooks,U. Schumacher Wydawnictwo: Humana Press Data wydania: 2001 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-610-9 Ilość stron: 0 Cena : 391 zł | |
Metastasis Research Protocols describes in detail all the methods needed to investigate why and how metastasis occurs. Volume I presents a comprehensive collection of established and leading-edge techniques for analyzing the expression of key molecules and for examining their production at the genetic level. The work focuses on the analysis and mapping of molecules produced by cells and tissues, and on the molecular biology underlying their expression. The traditional methods range from the histopathological and the immunocytochemical więcej... | ||
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Autor: Fan Chung Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-626-0 Ilość stron: 0 Cena : 391 zł | |
K. Fan Chung and Ian Adcock bring together the first collection of laboratory methods for studying the molecular and cellular mechanisms of asthma. Leading experts describe highly effective methods for obtaining cells from asthmatic airways, analyzing gene and protein expression in these clinical samples, and using molecular and cellular tools for studying cytokine expression and release in this disease. There are also cutting-edge techniques for studying asthma-related genes and genetic polymorphisms, and for understanding więcej... | ||
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Autor: Teicher Wydawnictwo: Humana Press Data wydania: 1998 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-641-3 Ilość stron: 0 Cena : 577.2 zł | |
Beverly Teicher and a panel of distinguished investigators survey the state-of-the-art of antiangiogenesis research from the lab bench to clinical trials. Timely and authoritative, the contributors summarize our current understanding of tumor growth and its dependence on vascular development, as well as the present status of antiangiogenic agents in preclinical and clinical development. In addition, the book also examines what is known about the mechanisms by which these therapeutic agents interfere with tumor vasculature więcej... | ||
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Autor: M. Markman Wydawnictwo: Humana Press Data wydania: 1999 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-729-8 Ilość stron: 0 Cena : 543.9 zł | |
Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a critical analysis of both the rationale and limitations of regional therapy and discuss potential clinical trials designed to explain the effectiveness of this method of therapy in special settings. Their presentations describe many exciting and innovative strategies for using regional więcej... | ||
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Autor: T. Yoshikawa Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-744-1 Ilość stron: 0 Cena : 410.6 zł | |
A panel of well known and highly experienced geriatric physicians and infectious disease experts review the most important common infections affecting the elderly and delineate their proven diagnostic, therapeutic, and preventive techniques for dealing with such common organ system problems as urinary tract infections, pneumonia, and ocular infections, as well as such specific microbial infections as tuberculosis, fungal, and viral infections. Also discussed are sepsis, infective endocarditis, intraabdominal infections, więcej... | ||
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Autor: P. Axelsen Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-760-1 Ilość stron: 0 Cena : 371.4 zł | |
Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, więcej... | ||
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Autor: D. Wang Wydawnictwo: Humana Press Data wydania: 2001 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-763-2 Ilość stron: 0 Cena : 583.1 zł | |
Donna Wang and a panel of hands-on experts describe in step-by-step detail all the major molecular, biochemical, and functional techniques now used in probing the renin-angiotensin system. These range from the use of embryonic gene targeting to create of mutant strains, to the functional investigation of components of the renin-angiotensin system. Comprehensive and highly practical, Angiotensin Protocols translates expert knowledge into readily reproducible methods that enable all biomedical investigators successfully to więcej... | ||
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Autor: J. Goedert Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-772-4 Ilość stron: 0 Cena : 563.5 zł | |
Goedert (viral epidemiology, National Cancer Institute) presents 27 surveys of those viruses, bacteria, and parasites that play a role in cancer. The contributors focus on various types of human carcinogenic infection including herpesviruses, retroviruses, papillomaviruses and hepatitis viruses. więcej... | ||
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Autor: R. Bukowski Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-781-6 Ilość stron: 0 Cena : 661.5 zł | |
More than 1200 individuals die from renal cell carcinoma on an annual basis in the US. During the 1990s a significant amount of the new information concerning the epidemiology, molecular and immunologic characteristics and therapy for patients with these tumours has appeared. In this text, Drs Bukowski and Novick and a core of expert clinicians highlight these advances thus enabling urologists, medical oncologists and radiation oncologists in their treatment of patients with renal cell carcinoma. They further explore novel więcej... | ||
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Autor: Wydawnictwo: Humana Press Data wydania: 2000 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-793-9 Ilość stron: 0 Cena : 504.7 zł | |
Leading experimental neurobiologists and neurosurgeons provide all the technical and practical information required to perform neural transplantation in experimental and neurological research, including a detailed consideration of the issues involved in designing and customizing such methods for specific research purposes. The authors outline the different sources of donor tissues and other materials for implantation, review the different techniques for tissue implantation into the brains of experimental animals of different więcej... | ||
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Autor: A. Weitberg Wydawnictwo: Humana Press Data wydania: 2001 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-830-1 Ilość stron: 0 Cena : 524.3 zł | |
This text provides contemporary information to oncologists and internists who diagnose and treat lung cancer. It opens with a primer on the molecular biology of lung cancer which enables the physician to understand the mechanisms behind the disease as well as the basis for the diagnostic tools and treatments that have become available. A section on practice guidelines instructs the reader in the methodology for the creation of practice guidelines and provides an understanding of how they are used in clinical practice. Treatment więcej... | ||
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Autor: Mattson Wydawnictwo: Humana Press Data wydania: 2001 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-838-7 Ilość stron: 0 Cena : 583.1 zł | |
In this groundbreaking book, leading experts detail the cellular and molecular cascades that cause selective degeneration of neuronal populations, and illuminate those genetic and environmental factors that are critical to the facilitation or suppression of the neuropathologic processes. Working from studies of human patients, as well as from cell culture and animal models, the authors demonstrate a heretofore unrecognized convergence of the causative pathogenetic mechanisms for clinically distinct neurological disorders więcej... | ||
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Autor: Hackett Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-892-9 Ilość stron: 0 Cena : 465.5 zł | |
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed więcej... | ||
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Autor: R. Elles,R. Mountford Wydawnictwo: Humana Press Data wydania: 2001 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-932-2 Ilość stron: 0 Cena : 387.1 zł | |
This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne muscular dystrophy. These largely generic methodologies may be adapted to most genetic conditions for which a molecular diagnosis is relevant, no matter how frequent or rare their incidence więcej... | ||
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Autor: Massaro Wydawnictwo: Humana Press Data wydania: 2002 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-936-0 Ilość stron: 0 Cena : 524.3 zł | |
Researchers and physicians in the fields of molecular genetics, neural development, obstetrics and gynecology, genetic and reproductive toxicology, pediatrics, cell biology and anatomy, nutrition sciences, and other fields offer a critical evaluation of the role of folate in human health and development. Specific areas addressed include folate metabolism in zinc or copper deficiencies, choline and folate in development, animal models of folate-related birth defects, developmental toxicants potentially acting via folate perturbation więcej... | ||
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Autor: S. Radovick Wydawnictwo: Humana Press Data wydania: 2003 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-946-9 Ilość stron: 0 Cena : 494.9 zł | |
An up-to-date and concise guide to the clinical management of pediatric endocrine disorders. The text covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and więcej... | ||
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Autor: Y. An Wydawnictwo: Humana Press Data wydania: 2003 Kategoria: medycyna i zdrowie ISBN: 978-0-89603-960-5 Ilość stron: 0 Cena : 616.4 zł | |
The first comprehensive collection of all the major methods for studying the histology and histomorphometry of bone and cartilage. The detailed methods include techniques for bone labeling, bone sectioning, histological analysis, histomorphometric analysis, radiological examination, and contact radiography. Among the applications presented are in situ hybridization of bone and cartilage, radiological examination of calcified tissue with emphasis on bone, and dealing with histology artifacts in hard tissue research. More więcej... | ||
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Autor: A. Klung,C. Jordan Wydawnictwo: Humana Press Data wydania: 2002 Kategoria: medycyna i zdrowie ISBN: 978-0-896038-12-7 Ilość stron: 0 Cena : 396.9 zł | |
Forty-one international specialists contribute 20 chapters to this volume, providing a variety of key laboratory methods for investigating hematopoietic stem cells (HSC). The text includes approaches using mouse and human tissues of both embryonic and adult origin, methods for the purification and genetic modification of stem cells, stem cell expansion protocols, and in vitro and in vivo assays, with techniques for studying a variety of stem cell topics, including blood formation, blood-based disease, and blood cancers such więcej... | ||
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Autor: M. Disis Wydawnictwo: Humana Press Data wydania: 2005 Kategoria: medycyna i zdrowie ISBN: 978-1-588-29564-4 Ilość stron: 0 Cena : 543.9 zł | |
Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens więcej... | ||
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Autor: E. Onaivi Wydawnictwo: Humana Press Data wydania: 2006 Kategoria: medycyna i zdrowie ISBN: 978-1-5882-9350-3 Ilość stron: 0 Cena : 387.1 zł | |
A cutting-edge collection of readily reproducible in vitro and in vivo methods to elucidate the mechanisms associated with cannabinoid function in health and disease. The techniques can be used in studies across the board from genes to behavior. The molecular neurobiological methods are invaluable in analyzing the structure, the polymorphisms, and the molecular expression of the cannabinoid receptors (CBrs), as well as their association with polysubstance abuse. There are also methods for localizing cannabinoid receptors więcej... | ||
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Autor: K. Turksen Wydawnictwo: Humana Press Data wydania: 2006 Kategoria: popularnonaukowe ISBN: 978-1-5882-9497-5 Ilość stron: 0 Cena : 420.4 zł | |
A comprehensive collection of diverse techniques for the molecular and cellular manipulation of human embryonic stem (hES) cells. These readily reproducible methods have been optimized for the derivation, characterization, and differentiation of hES cells, with special attention given to regenerative medicine applications. A companion CD provides color versions of all illustrations in the book. The protocols follow the successful Methods in Molecular BiologyŽ series format, each offering step-by-step laboratory instructions więcej... | ||
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Autor: Wheeler Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-005-2 Ilość stron: 0 Cena : 332.2 zł | |
Expert researchers who have developed and applied significant new assays describe in step-by-step detail a variety of methods for measuring a broad variety of hormones, related peptides, and synthetic steroids in various biological fluids. The hormones measured range from glucocorticoids in biological fluids, urinary steroids, aldosterone in blood, and plasma renin activity, to gut hormones in plasma, melatonin, prolactin, 6-sulfatoxymelatonin, and androgens in blood, saliva, and hair. The emphasis is on noncommercial assays więcej... | ||
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Autor: Charles Noback Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-039-7 Ilość stron: 0 Cena : 367.5 zł | |
Now in its sixth best-selling edition, The Human Nervous System: Structure and Function continues to combine clear prose with high quality tailor-made medical illustrations to achieve for neuroscientists and medical students a succinct explanation of the fundamental principles behind the organization, structure, and function of the human nervous system. The distinguished authors take advantage of the many recent advances in neurobiology and molecular biology to include new coverage of such critical discoveries as stem cells więcej... | ||
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Autor: A. Melville Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-062-5 Ilość stron: 0 Cena : 400.8 zł | |
Pioneering bench researchers describe in detail the cutting-edge techniques they have developed for analyzing the genomes and gene products in a diverse range of protozoan and metazoan parasites. These readily reproducible techniques can be used in genomic, functional genomic, and post-genomic studies and include transfection methods and vectors for several protozoan parasites, global analysis using microarrays, gene ablation using RNA interference, gene knockout, mutagenesis, and chromosome manipulation. Some of the protocols więcej... | ||
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Autor: Kelloff Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-077-9 Ilość stron: 0 Cena : 675.2 zł | |
Leading researchers comprehensively describe the exciting methodologies that are accelerating progress in chemoprevention and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design. The emphasis is on documenting the więcej... | ||
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Autor: P. Keohavong Wydawnictwo: Humana Press Data wydania: 2003 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-084-7 Ilość stron: 0 Cena : 469.4 zł | |
A collection of cutting-edge techniques for analyzing genotoxic exposure and detecting the resulting biological effects-including endogenous metabolites-up to and including the development of cancer. The authors emphasize analytical methods that can be specifically applied to human populations and patients. Among the applications detailed are the analysis of interactions between such cellular macromolecules as DNA and proteins and chemical and physical agents, the assessment of medically relevant toxicity, and the characterization więcej... | ||
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Autor: Su Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-107-3 Ilość stron: 0 Cena : 416.5 zł | |
This ambitious collection of essential yet novel methods for pancreatic cancer research or cancer research in general features an outstanding cast of authors who are esteemed leaders in the field. The authors provide a broad range of methods for molecular, biochemical, pathological, and statistical analysis of sporadic and familial pancreatic cancer, methods that can be applied not only to basic, but also to translational pancreatic research. Topics covered include in vitro cell cultures, in vivo mouse models, protein studies więcej... | ||
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Autor: L. Cheng Wydawnictwo: Humana Press Data wydania: 2002 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-118-9 Ilość stron: 0 Cena : 440 zł | |
This work provides an outlined-based, all inclusive reference of anatomic pathology for pathologists-in-training and practicing pathologists. Hundreds of tables and lists provide the pathologist with a concentrated reference on the diagnostic criteria and differential diagnosis required to ensure an accurate diagnosis. It is organised to allow for an easy reference for daily practice. The first part of the book covers general anatomic pathology, including diagnostic molecular pathology, medical cytogenetics, human genetic więcej... | ||
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Autor: Black Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-147-9 Ilość stron: 0 Cena : 622.3 zł | |
Recognized clinical leaders in neurosurgery and neuroradiology review the cutting-edge techniques and technologies now available and describe how minimally invasive techniques have influenced their subspecialties. On the radiology side, the authors explain the latest developments in magnetic resonance spectroscopy, functional imaging, and brain mapping, with emphasis on the application of image navigation directly in the operating room, using both preoperative and intraoperative systems. On the surgical side, some of the więcej... | ||
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Autor: R. Nakamura Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-167-7 Ilość stron: 0 Cena : 449.8 zł | |
High-profile laboratory scientists and basic cancer researchers review those recent and future clinical laboratory tests that can help in the early detection, evaluation, and prediction of human tumors, and so permit more informed therapeutic decisions. Emphasizing the importance of molecular and genetic RNA/DNA tests that can detect persons at high risk for specific cancers, the authors explore these novel serological assays, cellular assays useful for anatomic pathology, and molecular and genetic assays. Highlights include więcej... | ||
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Autor: Bell Wiley Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-199-8 Ilość stron: 0 Cena : 636 zł | |
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make więcej... | ||
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Autor: M. Runge Wydawnictwo: Humana Press Data wydania: 2006 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-202-5 Ilość stron: 0 Cena : 602.7 zł | |
This fully updated and expanded edition of the much-acclaimed Principles of Molecular Medicine provides an integrated survey of the basic principles of internal medicine, in light of recent dramatic discoveries in molecular medicine and new technologies for the diagnosis and treatment of human disease. In addition to fully revised sections on neurology, cardiology, hematology, nephrology, endocrinology, dermatology, immunology, gastroenterology, pulmonary disease, musculoskeletal medicine, and psychiatry, this volume contains więcej... | ||
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Autor: Lloyd Wydawnictwo: Humana Press Data wydania: 2003 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-208-7 Ilość stron: 0 Cena : 655.6 zł | |
A comprehensive review of recent molecular discoveries that can clarify the pathophysiology of endocrine disease processes and contribute to the diagnostic aspects of endocrine pathology. Surgeons, medical oncologists, and radiation therapists discuss the treatment of endocrine disorders, especially tumors, with emphasis on differential diagnosis and on broadening the perspective that the endocrine pathologist must have in making specific tissue diagnoses. Of interest to practicing pathologists, pathology residents, endocrinologists więcej... | ||
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Autor: Corti Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-223-0 Ilość stron: 0 Cena : 312.6 zł | |
A comprehensive collection of readily reproducible techniques for TNF production, characterization, mutagenesis, and detection in biological specimens. Also included are several in vitro assays and animal models for studying the role of TNF in various TNF-related diseases and in cancer. The collection offers molecular and cellular biologists, pharmacologists, and toxicologists a diverse set of versatile, cutting-edge tools for illuminating the pathophysiological roles of TNF in disease and for identifying new drugs. więcej... | ||
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Autor: D. Schoenberg Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-225-4 Ilość stron: 0 Cena : 308.7 zł | |
A collection of readily reproducible techniques for the study of mRNA processing and metabolism. These cutting-edge techniques range from cotranscriptional processing events that occur while the mNA is engaged with elongating RNA polymerase II, to in vivo and in vitro splicing and its biochemical analysis, and alternative splicing. Additional methods cover mRNA export, the recovery and analysis of mRNP complexes, cytoplasmic translation, mRNA degradation in vivo and in vitro, and the controversial concept of nuclear translation więcej... | ||
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Autor: A. Waldman Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: popularnonaukowe ISBN: 978-1-58829-236-0 Ilość stron: 0 Cena : 332.2 zł | |
Genetic recombination is any process in which DNA sequences interact and undergo a transfer of information, producing new "recombinant" sequences that contain information from each of the original molecules. This book presents leading peer-reviewed protocols to carry out recombinant investigations in the lab. Part I provides approaches and model systems for studying several aspects of recombination in a variety of eukaryotic organisms and in mammalian parasites. Part II describes approaches for using recombination więcej... | ||
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Autor: Barredo Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: popularnonaukowe ISBN: 978-1-58829-253-7 Ilość stron: 0 Cena : 416.5 zł | |
Leading experts in enzyme manipulation describe in detail their cutting-edge techniques for the screening, evolution, production, immobilization, and application of enzymes. These readily reproducible methods can be used to improve enzyme function by directed evolution, to covalently immobilize enzymes, to microencapsulate enzymes and cells, and to manufacture enzymes for human health, nutrition, and environmental protection. Overview chapters on microorganisms as a source of metabolic and enzymatic diversity, and on the więcej... | ||
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Autor: Wessells Wydawnictwo: Humana Press Data wydania: 2004 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-256-8 Ilość stron: 0 Cena : 381.2 zł | |
Practicing urologists and leading specialists summarize the optimal management of urgent and emergent urological conditions, so that physicians with limited urological training can take advantage of the incredible improvements in the management of acute urological problems. Up-to-date, evidence-based descriptions of the optimal diagnostic and therapeutic approaches cover a wide variety of conditions ranging from traumatic, infectious, and obstructive to hemorrhagic, iatrogenic, vascular, and congenital urological emergencies więcej... | ||
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Autor: G. Murray Wydawnictwo: Humana Press Data wydania: 2005 Kategoria: medycyna i zdrowie ISBN: 978-1-58829-260-5 Ilość stron: 0 Cena : 308.7 zł | |
Expert laboratorians noted for their optimized methods describe in step-by-step detail how to successfully carry out tissue-based laser microdissection in their own laboratory using the different systems available and to apply a wide range of sophisticated molecular technologies to the microdissected tissue samples. Highlights include gene expression profiling of primary tumor cell populations using laser capture microdissection, RNA transcript amplification and GeneChipŽ microarrays, laser capture microdissection and colorectal więcej... | ||
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Autor: G. Perdew Wydawnictwo: Humana Press Data wydania: 2007 Kategoria: popularnonaukowe ISBN: 978-1-58829-265-0 Ilość stron: 0 Cena : 367.5 zł | |
Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein. Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving więcej... | ||
